C2867
Cytochrome c from equine heart
BioUltra, ≥99% (SDS-PAGE), powder, suitable for mammalian cell culture
Manufacturer: Sigma Aldrich
CAS Number: 9007-43-6
Synonym(S): CYC, CytC, Cytochrome c from horse heart
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | C2867-10-MG | In Stock | ₹ 22,801.80 |
| 50 MG | C2867-50-MG | In Stock | ₹ 90,243.40 |
C2867 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 22,801.80
GST (18%): ₹ 4,104.324
Total Price: ₹ 26,906.124
biological source
horse heart
Quality Level
300
product line
BioUltra
Assay
≥99% (SDS-PAGE)
form
powder
mol wt
12,384
storage condition
(Tightly closed Dry)
technique(s)
cell culture | mammalian: suitable
solubility
water: 10 mg/mL, dark red-brown
UniProt accession no.
P00004
Other Options
Related Products
Description
- General description: Cytochrome C (Cyt C) is a nuclear DNA-encoded protein.[1] It is derived from its precursor apo-cytochrome c and moves across the outer membrane of the mitochondria.[2] Research area: Apoptosis
- Application: Cytochrome c from equine heart has been used to prepare a stock solution for synthesizing and calibrating biotinylated cytochrome c.[3] It has also been used as a component of the reaction buffer to stain electron transport chain (ETC) complex IV and determine its activity using blue-native gel electrophoresis.[4]
- Biochem/physiol Actions: Cytochrome C (Cyt C) acts as a potent signaling molecule of apoptosis by activating caspase 3, a death protease. It plays a role in heme-binding with the help of cytochrome c heme lyase which facilitates its release into the mitochondrial intermembrane space.[1] Cyt C also exhibits lipid-binding by interacting with cardiolipin, a phospholipid that initiates protein unfolding and activates the peroxidase function in Cyt C.[5]
- Preparation Note: A further purification of C2506
- Other Notes: View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves