G3643

α1-Acid Glycoprotein from bovine plasma

≥99%

Manufacturer: Sigma Aldrich

CAS Number: 66455-27-4

Synonym(S): Orosomucoid

Select a Size

Pack Size SKU Availability Price
25 MG G3643-25-MG In Stock ₹ 28,737.90
100 MG G3643-100-MG In Stock ₹ 78,510.30
250 MG G3643-250-MG In Stock ₹ 1,54,822.80

G3643 - 25 MG

₹ 28,737.90

In Stock

Quantity

1

Base Price: ₹ 28,737.90

GST (18%): ₹ 5,172.822

Total Price: ₹ 33,910.722

biological source

bovine plasma

Quality Level

200

Assay

≥99%

form

powder

technique(s)

electrophoresis: suitablemass spectrometry (MS): suitable

UniProt accession no.

Q3SZR3

storage temp.

2-8°C

Gene Information

bovine ... ORM1(497200)

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Description

  • General description: α1-Acid Glycoprotein (AGP, orosomucoid) from bovine plasma belongs to ‘lipocalins′ family which binds and transports small hydrophobic molecules. AGP is further classified into the subfamily ‘immunocalins′ which immunomodulates the inflammatory reactions.[1] AGP is primarily produced in the liver, in few extra hepatic tissues and is present in neutrophil granules. Healthy cattle possesses 0.3 mg of AGP/ ml of concentrated serum.[2]
  • Application: α1-Acid Glycoprotein (AGP) from bovine plasma has been used: in mass spectrometry analysis to confirm the presence of Neu5Ac and Neu5Gc distribution in human and bovine AGP respectively[4]for pretreating the microvessel before perfusing the MDA-MB-231 cells for tumor adhesion studies[5]in the composition of tear model[6]as a reference in sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE)[7]
  • Biochem/physiol Actions: α1-Acid Glycoprotein from bovine plasma is an acute phase protein. It has anti-inflammatory potential and its concentration increases several folds during injury. AGP increases the chemotactic activity and life span of monocytes and inhibits neutrophil degranulation.[2] Serum AGP levels differentiates sepsis from systemic inflammatory response syndrome (SIRS).[9]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves