Description

• Application: Design and development of a soluble PDA-Emodin-PVP-MN patch and its anti-obesity effect in rats.: This study presents the development of a microneedle patch containing Polyvinylpyrrolidone (PVP), which enhances the delivery of anti-obesity medication, showcasing PVP′s utility in pharmaceutical formulations to improve drug solubility and efficacy (Wang H et al., 2024).Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.: This research demonstrates the role of PVP, as a stabilizer and regulator in the synthesis of a nanodrug cocktail, indicating its critical function in nanomedicine for targeting and treating cancer effectively, thereby optimizing therapeutic outcomes (Wang C et al., 2024).Biochemical parameters, oxidative stress biomarkers, and anatomopathological changes in Wistar rats treated with 3′-demethoxy-6-O-demethylisoguaiacin and norisoguaiacin.: The study utilizes PVP in biomedical applications, particularly in enhancing the solubility and bioavailability of specific bioactive compounds for therapeutic purposes (Flores Jimenez NG et al., 2024).A water-soluble preparation for intravenous administration of isorhamnetin and its pharmacokinetics in rats.: Highlighting PVP′s importance in creating water-soluble drug formulations that facilitate the intravenous delivery of hydrophobic substances, this study explores its application in improving drug delivery systems (Rassu G et al., 2024).Activation of the PPAR gamma/NF-kB pathway by A-MPDA@Fe(3)O(4)@PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury.: This innovative study employs PVP to stabilize nanoparticle systems that actively participate in reducing oxidative stress, illustrating PVP′s potential in therapeutic interventions (Mo D et al., 2024).
• Other Notes: Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.