142077

2,2,2-Trichloroethyl chloroformate

98%

Manufacturer: Sigma Aldrich

CAS Number: 17341-93-4

Synonym(S): 2,2,2-Trichloroethoxycarbonyl chloride

Select a Size

Pack Size SKU Availability Price
25 G 142077-25-G In Stock ₹ 8,844.03
100 G 142077-100-G In Stock ₹ 22,505.18

142077 - 25 G

₹ 8,844.03

In Stock

Quantity

1

Base Price: ₹ 8,844.03

GST (18%): ₹ 1,591.925

Total Price: ₹ 10,435.955

vapor pressure

0.06 psi ( 20 °C)

Quality Level

200

Assay

98%

form

liquid

refractive index

n20/D 1.471 (lit.)

bp

171-172 °C (lit.)

density

1.539 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

ClC(=O)OCC(Cl)(Cl)Cl

InChI

1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2

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Description

  • General description: 2,2,2-Trichloroethyl chloroformate (TrocCl) serves as a versatile reagent used for selective acylation and dealkylation in organic synthesis. It is used in regio, chemo, and stereoselective synthesis.[1]
  • Application: 2,2,2-Trichloroethyl chloroformate was used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples[2].It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester[3].It was used as reagent during N-demethylation of dextromethorphan[4].It was used as protecting reagent for aliphatic and aromatic hydroxyl and amino groups[5].

SAFETY INFORMATION

Pictograms

GHS06,GHS05

Signal Word

Danger

Hazard Statements

H314,H331

Precautionary Statements

P280 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 + P310

Hazard Classifications

Acute Tox. 3 Inhalation - Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves