930547

Pomalidomide-PEG1-C2-azide

≥95.0%

Manufacturer: Sigma Aldrich

CAS Number: 2271036-44-1

Synonym(S): 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-azidoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl), 4-((2-(2-Azidoethoxy)ethyl]amino]-2-(2,6-dioxopiperidin-3-yl]isoindoline-1,3-dione, 4-[[2-(2-Azidoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

Select a Size

Pack Size SKU Availability Price
50 MG 930547-50-MG In Stock ₹ 18,670.00

930547 - 50 MG

₹ 18,670.00

In Stock

Quantity

1

Base Price: ₹ 18,670.00

GST (18%): ₹ 3,360.60

Total Price: ₹ 22,030.60

ligand

pomalidomide

Quality Level

100

Assay

≥95.0%

form

powder

functional group

azide

storage temp.

2-8°C

SMILES string

[N-]=[N+]=NCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Pomalidomide 4'-PEG1-azide
-- ₹ 23,486.22
eMolecules​ Medchem Express / Pomalidomide-PEG1-C2-N3 / 25mg / 649421571 / HY-125843 / / 2271036-44-1 / [null] / 386.368 / C17H18N6O5
-- ₹ 23,299.70
Pomalidomide-PEG1-C2-N3
-- ₹ 4,962.48 - ₹ 43,122.24
Pomalidomide-PEG1-C2-N3
-- ₹ 15,828.60
2271036-44-1 | POMALIDOMIDE-PEG1-C2-N3
-- ₹ 14,459.64 - ₹ 69,474.72

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Description

  • Application: Pomalidomide-PEG1-C2-azide is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Contains an alkyne, allowing for conjugation through click chemistry. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Protein Degrader Building Blocks
  • Other Notes: Targeted Protein Degradation by Small Molecules Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable