Description

• General description: Borane dimethyl sulfide complex (BMS) is a commonly used reagent and a mediator for hydroboration reaction for the preparation of organoborane compounds, which are utilized as key intermediates in organic synthesis. BMS is also employed as a reducing agent for the reduction of various functional groups such as aldehydes, ketones, epoxides, esters, and carboxylic acids to corresponding alcohols.[1][2]
• Application: Borane-dimethyl sulfide (BH3 Me2S) can be used as a reagent: For the selective synthesis of 1,3,5-oxygenated compounds from dimethyl 3-oxoglutarate.[3] For the conversion of ozonides to alcohols.[4] In the CBS-catalyzed asymmetric reduction of ferrocenyl-1,3-diketones to 1,3-diols.[5] For enantioselective reduction of ketones to chiral secondary alcohols in the presence of C3-symmetric tripodal hydroxyamide as a ligand.[6] For the hydroboration reduction and other applications.[7][8] With a dendrimeric supported L-pyrrolidinol in the asymmetric reduction of indanones and tetralones.[9]
• Packaging: The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.
• Other Notes: 10.0-10.2 M as BH3. May contain excess methyl sulfide.
• Legal Information: Sure/Seal is a trademark of Sigma-Aldrich Co. LLC