526797

Cyclopropylmagnesium bromide solution

0.5 M in THF

Manufacturer: Sigma Aldrich

CAS Number: 23719-80-4

Synonym(S): Bromocyclopropylmagnesium

Select a Size

Pack Size SKU Availability Price
100 ML 526797-100-ML In Stock ₹ 46,428.43
800 ML 526797-800-ML In Stock ₹ 1,69,855.08

526797 - 100 ML

₹ 46,428.43

In Stock

Quantity

1

Base Price: ₹ 46,428.43

GST (18%): ₹ 8,357.117

Total Price: ₹ 54,785.547

reaction suitability

reaction type: Grignard Reaction

Quality Level

100

concentration

0.5 M in THF

bp

65 °C

density

0.968 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

Br[Mg]C1CC1

InChI

1S/C3H5.BrH.Mg/c1-2-3-1;;/h1H,2-3H2;1H;/q;;+1/p-1

InChI key

QUPLLJGAJVXXBW-UHFFFAOYSA-M

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Description

  • Application: Cyclopropylmagnesium bromide solution has been used in Grignard reaction that finds application as the key step in the preparation of aminopropylindenes, a chemotype of oxidosqualene cyclase (OSC) inhibitors from Grundmann′s ketone.[1] It can react with trimethylborate to form cyclopropylboronic acid, which can undergo Suzuki-type coupling reactions with different aryl, and heteroaryl bromides to form the cyclopropyl adducts.[2]

SAFETY INFORMATION

Pictograms

GHS02,GHS08,GHS05,GHS07

Signal Word

Danger

Hazard Statements

H225,H261,H302,H314,H335,H336,H351

Precautionary Statements

P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 2

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

WGK

WGK 3

Flash Point(F)

1.0 °F

Flash Point(C)

-17.22 °C