746061

Difluoromethyl 2-pyridyl sulfone

97% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 1219454-89-3

Synonym(S): 2-[(Difluoromethyl)sulfonyl]pyridine, Hu Reagent, 2-(Difluoromethylsulfonyl)pyridine, 2-PySO2CF2H

Select a Size

Pack Size SKU Availability Price
1 G 746061-1-G In Stock ₹ 9,471.88
5 G 746061-5-G In Stock ₹ 44,339.20

746061 - 1 G

₹ 9,471.88

In Stock

Quantity

1

Base Price: ₹ 9,471.88

GST (18%): ₹ 1,704.938

Total Price: ₹ 11,176.818

Quality Level

100

Assay

97% (HPLC)

form

solid

mp

44-49 °C

SMILES string

O=S(C1=CC=CC=N1)(C(F)F)=O

InChI

1S/C6H5F2NO2S/c7-6(8)12(10,11)5-3-1-2-4-9-5/h1-4,6H

InChI key

YRQNSTAWTLXCEZ-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
Sigma Aldrich Fine Chemicals Biosciences Difluoromethyl 2-pyridyl sulfone 97% (HPLC) | 1219454-89-3 | MFCD17010193 | 5G
-- ₹ 66,937.01
2-[(Difluoromethyl)sulfonyl]pyridine
-- ₹ 342.24 - ₹ 67,421.28
Difluoromethyl 2-pyridyl sulfone
-- ₹ 598.92 - ₹ 24,470.16

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Description

  • General description: Difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H) is a reagent used in the gem-difluoroolefination of aldehydes and ketones. It is also used as a reagent in the nucleophilic difluoro(sulfonato)methylation of alcohols, N-sulfinyl imines, and halides.[1][2]
  • Application: Reagent is used in the olefination of ketones and aldehydes to form gem-difluoro olefins under basic conditions.[3] Product is also used as a crucial intermediate toward making 1,1-difluorinated alkyl chains for the alkylation of heterocycles.[4]

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H301,H319

Precautionary Statements

P264 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313 - P405

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable