21-511-0R
Tocris Bioscience™ API-2
Manufacturer: Tocris Bioscience™
CAS Number: 35943-35-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 21-511-0R-Each-of-1 | In Stock | ₹ 40,127.64 |
21-511-0R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,127.64
GST (18%): ₹ 7,222.975
Total Price: ₹ 47,350.615
Purity
99%
CAS
35943-35-2
Gene Alias
Triciribine, NSC 154020, TCN
Product Type
API-2
Inhibitors
API-2
Molecular Formula
1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine
Content And Storage
Room Temperature
Quantity
10 mg
Molecular Weight (g/mol)
M.W. (Observed): 320.31
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ Akt Inhibitor V, Triciribine | -- | -- | |
| | MilliporeSigma™ Calbiochem™ Akt Inhibitor V, Triciribine | -- | ₹ 24,076.58 | |
| | MilliporeSigma™ Calbiochem™ Akt Inhibitor V, Triciribine | -- | ₹ 52,183.90 | |
| | Medchemexpress LLC HY-15457 10mg , Triciribine CAS:35943-35-2 Purity:>98% | -- | ₹ 15,092.78 | |
| | Medchemexpress LLC HY-15457 5mg Medchemexpress, Triciribine CAS:35943-35-2 Purity:>98% | -- | ₹ 9,522.83 | |
| | Apexbio Technology LLC DNA synthesis, Akt and HIV-1 inhibitor 35943-35-2. MFCD00932413 | -- | ₹ 7,272.60 | |
| | 35943-35-2 | API-2 | -- | ₹ 3,679.08 - ₹ 38,330.88 |
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Description
- API-2 is a selective inhibitor of Akt (protein kinase B) signaling; displays minimal inhibition of PKC, PKA, SGK and p38 pathways
- Inhibits phosphorylation and activation of downstream targets of Akt including Bad, GSK-3β and AFX
- Induces apoptosis and growth arrest in vitro , preferentially in human cancer cells with elevated levels of Akt
- Potently and selectively inhibits growth of Akt-overexpressing tumors in mice
- Inhibits DNA synthesis and displays antiviral activity against HIV-1 and -2.