35-995-0R

Tocris Bioscience™ TAK 165

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 35-995-0R-Each-of-1 In Stock ₹ 99,249.60

35-995-0R - Each of 1

₹ 99,249.60

In Stock

Quantity

1

Base Price: ₹ 99,249.60

GST (18%): ₹ 17,864.928

Total Price: ₹ 1,17,114.528

Purity

>99%

Quantity

50 mg

Molecular Weight (g/mol)

468.47

Gene Alias

Mubritinib

Product Type

TAK 165

Inhibitors

TAK 165

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Description

  • Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src
  • Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .