50-685-0R

Tocris Bioscience™ ITD 1

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-685-0R-Each-of-1 In Stock ₹ 1,19,441.76

50-685-0R - Each of 1

₹ 1,19,441.76

In Stock

Quantity

1

Base Price: ₹ 1,19,441.76

GST (18%): ₹ 21,499.517

Total Price: ₹ 1,40,941.277

Purity

>98%

Quantity

50 mg

Molecular Weight (g/mol)

415.52

Content And Storage

-20°C

Product Type

ITD 1

Inhibitors

ITD 1

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Description

  • Selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways
  • Induces proteasomal degradation of the TGF-β type II receptor
  • Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5
  • Does not induce differentiation of vascular smooth muscle cells or endothelial cells.