36-065-0R

Tocris Bioscience™ BAG 956

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 36-065-0R-Each-of-1 In Stock ₹ 1,32,446.88

36-065-0R - Each of 1

₹ 1,32,446.88

In Stock

Quantity

1

Base Price: ₹ 1,32,446.88

GST (18%): ₹ 23,840.438

Total Price: ₹ 1,56,287.318

Purity

98%

Quantity

50 mg

Molecular Weight (g/mol)

427.5

Content And Storage

Store at -20°C

Product Type

BAG 956

Inhibitors

BAG 956

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Description

  • Dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively)
  • Inhibits cellular AKT phosphorylation at Thr308
  • Blocks cell proliferation, causing arrest in G1 phase of the cell cycle
  • Slows tumor progression in mouse xenograft models.