51-101-0

Tocris Bioscience™ GSK 1562590 hydrochloride

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 51-101-0-Each-of-1 In Stock ₹ 36,491.34

51-101-0 - Each of 1

₹ 36,491.34

In Stock

Quantity

1

Base Price: ₹ 36,491.34

GST (18%): ₹ 6,568.441

Total Price: ₹ 43,059.781

Purity

>98%

Product Type

GSK 1562590 hydrochloride

Inhibitors

GSK 1562590 hydrochloride

Quantity

10 mg

Molecular Weight (g/mol)

617.95

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Description

  • High affinity and selective urotensin II (UT) receptor antagonist (pKi values are 9.14, 9.28, 9.34, 9.64 and 9.66 at monkey, human, mouse, cat and rat recombinant receptors respectively)
  • Exhibits selectivity for UT receptors over a range of GPCRs, ion channels, enzymes and neurotransmitter transporters
  • Supresses human urotensin-II (hU-II)-induced contraction of isolated rat aorta in vitro and ex vivo
  • Inhibits the hU-II-induced increase in mean blood pressure in vivo
  • Orally active.