52-641-0
Tocris Bioscience™ Temsirolimus
Manufacturer: Tocris Bioscience™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 52-641-0-Each-of-1 | In Stock | ₹ 22,202.82 |
52-641-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,202.82
GST (18%): ₹ 3,996.508
Total Price: ₹ 26,199.328
Purity
>98%
Quantity
10 mg
Molecular Weight (g/mol)
1030.29
Gene Alias
CCI-779
Product Type
Temsirolimus
Inhibitors
Temsirolimus
Related Products
Description
- Temsirolimus is a mTOR inhibitor; inhibits tumor growth in breast cancer cell lines (IC50 values are 1.6 and 4.3 nM for SKBr3 and BT474, respectively)
- Inhibits HIF-1α-mediated VEGF production in breast cancer cell lines (BT474 and MDA-MB-231)
- Directly inhibits serum and VEGF mediated endothelial cell proliferation and morphogenesis in vitro and vessel formation in vivo
- Causes G1/S cell cycle arrest in multiple cancer cell lines
- Antiangiogenic
- Activates autophagy.