36-311-0R
Tocris Bioscience™ FK 506
Manufacturer: Tocris Bioscience™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 36-311-0R-Each-of-1 | In Stock | ₹ 21,475.56 |
36-311-0R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,475.56
GST (18%): ₹ 3,865.601
Total Price: ₹ 25,341.161
Purity
>99%
Quantity
10 mg
Molecular Weight (g/mol)
804.02
Gene Alias
Tacrolimus, Fujimycin
Product Type
FK 506
Inhibitors
FK 506
Related Products
Description
- FK 506 is a potent calcineurin (protein phosphatase 2B) inhibitor that requires FK 506-binding protein 12 (FKBP12) for activity (IC50 = 3 nM)
- Inhibits secretion of IL-1, IL-2 (IC50 = 1 nM), IL-3, IL-4, IL-6 (IC50 = 35 nM), GM-CSF, TNFα (IC50 = 10 nM), IFNγ and Myc from activated T cells in vitro
- Exhibits potent immunosuppressive, neuroprotective and anticonvulsant activity in vivo
- Identified as targeting human host cell proteins that interact with SARS-CoV-2
- Analog also available.