5545765

Tocris Bioscience™ DBM 1285 dihydrochloride

p38 MAPK inhibitor; anti-inflammatory

Manufacturer: Fischer Scientific

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Purity

>98%

Product Type

DBM 1285 dihydrochloride

Molecular Weight (g/mol)

468.42

Inhibitors

DBM 1285 dihydrochloride

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Description

  • DBM 1285 dihydrochloride is a p38 MAPK inhibitor
  • Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo
  • Attenuates zymosan-induced inflammation and adjuvant-induced arthritis in murine models
  • Orally active.