5545865
Tocris Bioscience™ LM11A 31 dihydrochloride
Nonpeptide p75NTR ligand; neuroprotective
Manufacturer: Fischer Scientific
CAS Number: 1243259-19-9
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Purity
95%
CAS
1243259-19-9
Product Type
LM11A 31 dihydrochloride
Inhibitors
LM11A 31 dihydrochloride
Molecular Formula
(2 S,3 S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride
Content And Storage
Desiccate at RT
Molecular Weight (g/mol)
M.W. (Observed): 316.27
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC LM11A-31 dihydrochloride | 1243259-19-9 | MFCD28166485 | 100mg | -- | ₹ 44,469.81 | |
| | eMolecules Medchem Express / LM11A-31 (dihydrochloride) / 5mg / 489862970 / HY-110155 / / 1243259-19-9 / MFCD28166485 / 316.270 / C12H27Cl2N3O2 | -- | ₹ 6,926.94 | |
| | Tocris Bioscience™ LM11A 31 dihydrochloride | -- | ₹ 61,260.96 | |
| | Tocris Bioscience™ LM11A 31 dihydrochloride | -- | ₹ 14,836.10 | |
| | Pentanamide, 2-amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-, hydrochloride (1:2), (2S,3S)- | -- | ₹ 5,646.96 - ₹ 6,930.36 | |
| | 1243259-19-9 | Pentanamide, 2-amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-, hydrochloride (1:2), (2S,3S)- | -- | ₹ 3,850.20 - ₹ 15,400.80 |
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Description
- Nonpeptide p75NTR ligand; blocks p75-mediated cell death and also increases proliferation and survival of hippocampal neural progenitors
- Exhibits no effect on nerve growth factor (NGF) binding to TrkA
- Prevents and reverses atrophy of cholinergic neurites, as well as reversing Alzheimer's Disease (AD) pathologies in mid- to late-stage AD mice models
- Shown to promote functional recovery in a mouse model of spinal cord injury
- Orally available and brain penetrant.