5545942
Tocris Bioscience™ OF 1
Selective BRPF1B and BRPF2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 919973-83-4
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Purity
98%
CAS
919973-83-4
Product Type
OF 1
Inhibitors
OF 1
Molecular Formula
4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1 H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
Content And Storage
4°C
Molecular Weight (g/mol)
M.W. (Observed): 440.31
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ OF 1 | -- | ₹ 22,430.41 | |
| | Tocris Bioscience™ OF 1 | -- | ₹ 91,011.88 | |
| | OF-1 | -- | ₹ 14,970.98 | |
| | 919973-83-4 | Of-1 | -- | ₹ 1,711.20 - ₹ 33,368.40 |
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Description
- Selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively)
- Exhibits 39-fold selectivity for BRPF1B and BRPF2 over BRD4
- Accelerates FRAP recovery at 5 μM in a BRPF2 FRAP assay
- Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.