5545896

Tocris Bioscience™ MPC 6827 hydrochloride

Inhibitor of microtubule polymerization; antimitotic and antitumor

Manufacturer: Fischer Scientific

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Purity

>98%

Product Type

MPC 6827 hydrochloride

Molecular Weight (g/mol)

315.8

Inhibitors

MPC 6827 hydrochloride

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Description

  • Potent inhibitor of microtubule formation (IC50 = 1.5 - 3.4 nM); inhibits polymerization of tubulin in vitro and disrupts microtubule formation in several cancer cell lines
  • Inhibits tumor growth in vitro and in vivo ; exhibits pro-apoptotic characteristics
  • Brain penetrant.