5546109
Tocris Bioscience™ Xanomeline oxalate
Functionally selective M1 agonist
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
Xanomeline oxalate
Molecular Weight (g/mol)
371.46
Inhibitors
Xanomeline oxalate
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Description
- Description Functionally selective muscarinic M1 receptor agonist (EC50 values are 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively)
- Displays a complex pharmacological profile: reversible and wash-resistant binding, resulting in full agonist activity at M1; delayed wash-resistant partial agonist activity at M2; and delayed wash-resistant full agonist activity at M4
- Exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.