49-045-0
Tocris Bioscience™ UNC 1999
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 49-045-0-Each-of-1 | In Stock | ₹ 1,12,682.52 |
49-045-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,12,682.52
GST (18%): ₹ 20,282.854
Total Price: ₹ 1,32,965.374
Purity
>99%
Product Type
UNC 1999
Inhibitors
UNC 1999
Quantity
50 mg
Molecular Weight (g/mol)
569.74
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Description
- Potent and SAM-competitive EZH2/EZH1 lysine methyltransferase inhibitor (IC50 values are 10 and 45 nM, respectively)
- Selective for EZH2/EZH1 over a panel of other methyltransferases and non-epigenetic targets
- Reduces H3K27me3 levels in vitro
- Prolongs survival of MLL-AF9 bearing mice
- Orally bioavailable
- Negative Control also available.