51-215-0
Tocris Bioscience™ 3PO
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 51-215-0-Each-of-1 | In Stock | ₹ 50,052.60 |
51-215-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,052.60
GST (18%): ₹ 9,009.468
Total Price: ₹ 59,062.068
Purity
>99%
Product Type
3PO
Inhibitors
3PO
Quantity
50 mg
Molecular Weight (g/mol)
210.23
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Description
- Originally reported to inhibit PFKFB3 (IC50 = 25 μM)
- More recent reports failed to demonstrate activity in a PFKFB3 kinase assay
- Reduces glycolytic flux and suppresses glucose uptake
- Inhibits endothelial cell proliferation and causes G2/M cell cycle arrest in vitro
- Attenuates vessel sprouting and tumor growth in vivo
- Amplifies the antiangiogenic effect of VEGFR blockade.