53-185-0
Tocris Bioscience™ AEE 788
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-185-0-Each-of-1 | In Stock | ₹ 1,31,505.72 |
53-185-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,31,505.72
GST (18%): ₹ 23,671.03
Total Price: ₹ 1,55,176.75
Purity
>98%
Product Type
AEE 788
Inhibitors
AEE 788
Quantity
50 mg
Molecular Weight (g/mol)
440.58
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Description
- Potent EGFR and VEGFR inhibitor (IC50 values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively)
- Also inhibits c-Abl, c-Fms and c-Src (IC50 values are 52, 60 and 61 nM respectively)
- Inhibits proliferation of EGFR and ErbB2 overexpressing cancer cell lines in vitro
- Inhibits tumor xenograft growth and VEGF-induced angiogenesis in mice
- Orally active.