5546127

Tocris Bioscience™ A12B4C3

Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

A12B4C3

Molecular Weight (g/mol)

534.65

Inhibitors

A12B4C3

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Description

  • Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor (IC50 = 60 nM)
  • Displays no effect on calcineurin, protein PP-1 or APTX
  • Interrupts DNA repair and enhances radiosensitivity of human A549 lung carcinoma and MDA-MB-231 cells.