5546144

Tocris Bioscience™ CCG 1423

Induces intermediate mesoderm differentiation from ESCs; Rho/SRF pathway inhibitor

Manufacturer: Fischer Scientific

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Purity

>99%

Product Type

CCG 1423

Molecular Weight (g/mol)

454.75

Inhibitors

Rho GTPase Inhibitors

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Description

  • Rho/SRF pathway inhibitor; stimulates apoptosis of a melanoma cell line overexpressing RhoC (A375M2)
  • Suppresses Rho-dependent invasion of PC-3 prostate cancer cells in vitro and inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer cells
  • When used in combination with Retinoic acid, LY 294002 and Pyridone 6, it induces intermediate mesoderm differentiation from ESCs.