7075671
CCF4-AM
CCF4-AM
Manufacturer: Fischer Scientific
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Cell Permeability
Cell-Permeant
Detection Method
Fluorescence
Substrate
CCF4-AM
Substrate Type
Beta-Lactamase Substrate
Shipping Condition
Room Temperature
Content And Storage
Store in freezer (-5 to -30°C).
Form
Solid
Substrate Properties
Chemical Substrate
For Use With (Equipment)
Flow Cytometer, Microplate Reader
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Description
- CCF4-AM, our LiveBLAzer™ substrate, is a lipophilic, esterified form of the CCF4 substrate which allows it to readily enter cells
- Upon entry, cleavage by endogenous cytoplasmic esterases rapidly converts CCF4-AM into its negatively charged form, CCF4, which is retained in the cytosol
- CCF4 is a Fluorescence Resonance Energy Transfer (FRET) substrate which consists of a cephalosporin core linking 7-hydroxycoumarin to fluorescein
- This product is to be used as a FRET-based substrate for β-lactamase as a sensitive reporter of mammalian gene expression in the GeneBLAzer™ technology.