21-967-55MG
MilliporeSigma™ Calbiochem™ InSolution™ CFTR Inhibitor II, GlyH-101
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 21-967-55MG-Each-of-1 | In Stock | ₹ 21,421.66 |
21-967-55MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,421.66
GST (18%): ₹ 3,855.899
Total Price: ₹ 25,277.559
Formulation
A 25 mM (5mg/406μL) solution of CFTR Inhibitor II, GlyH-101 in DMSO.
Target Proteins
CFTR
Formula Weight
493.2g/mol
Form
Liquid
Description
97% by HPLC
Molecular Formula
C19H15Br2N3O3
Content And Storage
Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light
Quantity
5 mg
Related Products
Description
- A cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (<1 min; 95% inhibition at 50μM; K i = 4.3μM in CFTR-expressing FRT cells for apical membrane Cl - current) and exhibits desirable aqueous solubility
- Shown to produce inwardly rectifying CFTR Cl - currents with reduced mean channel open time and suggested to directly interact with the channel pore at the extracellular side of the membrane
- Displays minimal effects on P-glycoprotein and non-CFTR-mediated Cl - currents, and is effective in nasal and intestinal epithelia in vivo .