23-449-1500UG

MilliporeSigma™ Calbiochem™ InSolution™ PD 153035

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 23-449-1500UG-Each-of-1 In Stock ₹ 15,229.68

23-449-1500UG - Each of 1

₹ 15,229.68

In Stock

Quantity

1

Base Price: ₹ 15,229.68

GST (18%): ₹ 2,741.342

Total Price: ₹ 17,971.022

Formulation

A 10 mM (500μg/139μl) solution of PD 153035 in DMSO.

Target Proteins

EGFR

Formula Weight

360.2g/mol

Form

Liquid

Description

97% by HPLC

Molecular Formula

C16H14BrN3O2

Content And Storage

Hygroscopic, Protect from light

Quantity

500 μg

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Description

  • An extremely potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM; Ki = 6 pM)
  • Rapidly suppresses autophosphorylation of EGFR at low nanomolar concentrations in fibroblasts or in human epidermoid carcinoma cells
  • Also selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation.