42-017-510MG
MilliporeSigma™ Calbiochem™ Cancer Hydrolase KIAA1363 Inhibitor, JW480
Manufacturer: MilliporeSigma™
CAS Number: 1354359-53-7
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 42-017-510MG-Each-of-1 | In Stock | ₹ 12,748.44 |
42-017-510MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,748.44
GST (18%): ₹ 2,294.719
Total Price: ₹ 15,043.159
Color
White
CAS
1354359-53-7
Formula Weight
333.4g/mol
Content And Storage
Protect from light
Quantity
10 mg
Description
97% by HPLC
Molecular Formula
C22H23NO2
Solubility
DMSO
Form
Powder
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences JW480 >=98% (HPLC) | 1354359-53-7 | 25MG | -- | ₹ 50,925.31 | |
| | 1354359-53-7 | JW 480 | -- | ₹ 4,363.56 - ₹ 37,731.96 |
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Description
- A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC 50 = 12nM; PC3 lysate) and murine (IC 50 = 20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE
- Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.)
- Also inhibits blood carboxylesterase.