56-773-210MG
MilliporeSigma™ Calbiochem™ Sphingosine Kinase 1 Inhibitor, SKI-178
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-773-210MG-Each-of-1 | In Stock | ₹ 16,024.53 |
56-773-210MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,024.53
GST (18%): ₹ 2,884.415
Total Price: ₹ 18,908.945
Color
Off-white
Molecular Formula
C21H22N4O4
Solubility
DMSO
Form
Powder
Description
92% by HPLC
Formula Weight
394.4g/mol
Content And Storage
Protect from light
Quantity
10 mg
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Description
- A cell-permeable pyrazolocarbohydrazide compound that acts as a potent, reversible, sphingosine competitive and ATP-non-competitive inhibitor of sphingosine kinase 1 (SphK1) activity with excellent selectivity over SphK2 (K i = 1.33 and >> 25μM, respectively)
- Shown to suppress sphingosine-1-phosphate (S1P) production in A549 cells and efficiently induce apoptosis in several tumor cells (IC 50 in the range of 0.1-1.8μM).