42-029-410MG

MilliporeSigma™ Calbiochem™ STAT5 Inhibitor II, IQDMA

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 42-029-410MG-Each-of-1 In Stock ₹ 16,024.53

42-029-410MG - Each of 1

₹ 16,024.53

In Stock

Quantity

1

Base Price: ₹ 16,024.53

GST (18%): ₹ 2,884.415

Total Price: ₹ 18,908.945

Color

Brown

Molecular Formula

C19H20N4

Solubility

DMSO

Quantity

10 mg

Description

95% by HPLC

Formula Weight

304.39g/mol

Form

Solid

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Description

  • A cell-permeable indoloquinoline compound that exhibits anticancer activity and inhibits the growth of A549 lung cancer cells (IC 50 = 8μM), as well as HL-60 (IC 50 = 5μM) and K562 (IC 50 = 8μM) leukemia cells
  • IQDMA-mediated apoptosis is shown to correlate with a downregulation of STAT5 pathway signaling in HL-60 and K562 cultures, while JNK and p38 signalings are shown to be activated in A549 cells upon IQDMA treatment.