47-584-610MG

MilliporeSigma™ Calbiochem™ MIF Antagonist III, 4-IPP

Manufacturer: MilliporeSigma™

CAS Number: 41270-96-6

Select a Size

Pack Size SKU Availability Price
Each of 1 47-584-610MG-Each-of-1 In Stock ₹ 14,736.00

47-584-610MG - Each of 1

₹ 14,736.00

In Stock

Quantity

1

Base Price: ₹ 14,736.00

GST (18%): ₹ 2,652.48

Total Price: ₹ 17,388.48

Color

Amber

CAS

41270-96-6

Formula Weight

282.1g/mol

Content And Storage

Protect from light

Quantity

10 mg

Description

90% by HPLC

Molecular Formula

C10H7IN2

Solubility

DMSO

Form

Solid

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Description

  • A cell-permeable iodo-pyrimidine compound that covalently modifies MIF N-terminal proline and exhibits higher MIF inhibitory potency than ISO-1 (Cat
  • No
  • 475837) in cell-free dopachrome tautomerase activity assays (IC 50 ∽5 vs
  • 50μM, respectively, using recombinant human MIF) as well as in cell-based migration assays (50% vs 0% inhibition with respective inhibitor at 10μM) and anchorage-independent growth (57% vs 0% inhibition with respective inhibitor at 10μM) using human lung adenocarcinoma A549
  • Also shown to reduce A549 cellular active Rac1 population (50μM, 16 h) in vitro and effectively decrease liver tautomerase activity by 50% in mice (1mg/animal/day or ∽50mg/kg/day via i.p.) in vivo .