50-055-40001
MilliporeSigma™ Calbiochem™ mTOR Activator, MHY1485
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-055-40001-Each-of-1 | In Stock | ₹ 18,340.64 |
50-055-40001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,340.64
GST (18%): ₹ 3,301.315
Total Price: ₹ 21,641.955
Color
Pale Yellow
Molecular Formula
C17H21N7O4
Solubility
DMSO
Form
Solid
Description
97% by HPLC
Formula Weight
387.39g/mol
Content And Storage
Protect from light
Quantity
10 mg
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Description
- A cell-permeable triazine derivative that is shown to increase cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation level in rat liver Ac2F cells (1 to 2μM for 1 h), affecting culture viability only at much higher concentrations (by 20% after 24 h 20μM treatment)
- MHY1485 induced cellular LC3-II accumulation in Ac2F is reported to be a result of autophagy inhibition due to reduced fusion between autophagosomes and lysosomes
- The mechanism of mTOR activation by MHY1485 is currently unknown.