50-522-50001
MilliporeSigma™ Calbiochem™ InSolution™ MIF Antagonist, ISO-1
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-522-50001-Each-of-1 | In Stock | ₹ 19,879.01 |
50-522-50001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 19,879.01
GST (18%): ₹ 3,578.222
Total Price: ₹ 23,457.232
Formulation
A 50 mM (10mg/850μL) sterile-filtered solution of MIF Antagonist, ISO-1 in DMSO.
Target Proteins
MIF dopachrome tautomerase
Formula Weight
235.2g/mol
Form
Liquid
Description
95% by HPLC
Molecular Formula
C12H13NO4
Content And Storage
Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light
Quantity
10 mg
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Description
- A cell-permeable isoxazoline compound that displays anti-inflammatory properties
- Inhibits MIF dopachrome tautomerase activity by binding to its catalytic active site (IC 50 = 7μM for D-dopachrome tautomerase) and suppresses the production of TNFα, PGE 2 and COX-2 in human monocytes and arachidonic acid in RAW 264.7 macrophages
- Shown to exhibit antidiabetogenic properties in immunoinflammatory diabetic mouse model.