50-573-60001
MilliporeSigma™ Calbiochem™ 5-BDBD
Manufacturer: MilliporeSigma™
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Color
Off-white
Target Proteins
P2X4
Solubility
DMSO
Form
Powder
Description
99% by HPLC
Molecular Formula
C17H11BrN2O2
Content And Storage
Protect from light
Quantity
5 mg
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Description
- A highly potent antagonist of purinergic P2X 4 receptor
- Shown to block P2X 4 -mediated currents in Chinese hamster ovary cells (IC 50 = 500nM)
- Blocks ATP-induced dilation of spiral ligament capillaries in guinea pigs
- Also shown to restore the viability of activated CD4+ cells in the presence of 1mm ATP.