55-351-010MG

MilliporeSigma™ Calbiochem™ RAD51-Stimulatory Compound-1, RS-1

Manufacturer: MilliporeSigma™

CAS Number: 312756-74-4

Select a Size

Pack Size SKU Availability Price
Each of 1 55-351-010MG-Each-of-1 In Stock ₹ 14,393.76

55-351-010MG - Each of 1

₹ 14,393.76

In Stock

Quantity

1

Base Price: ₹ 14,393.76

GST (18%): ₹ 2,590.877

Total Price: ₹ 16,984.637

Color

Light Beige

CAS

312756-74-4

Formula Weight

524.2g/mol

Content And Storage

Protect from light

Quantity

10 mg

Description

95% by HPLC

Molecular Formula

C20H16Br2N2O3S

Solubility

DMSO or EtOH

Form

Solid

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ RS 1
-- --
Medchemexpress LLC HY-19793 5mg Medchemexpress, RS-1 CAS:312756-74-4 Purity:>98%
-- ₹ 5,390.28
Cayman Chemical RS-1, 312756-74-4, 10 mg
-- ₹ 5,608.46
Sigma Aldrich Fine Chemicals Biosciences RS-1 >=98% (HPLC) | 312756-74-4 | MFCD00348720 | 25MG
-- ₹ 47,434.46
312756-74-4 | Rs-1
-- ₹ 2,481.24 - ₹ 31,828.32

Related Products

Img

MilliporeSigma™

50-616-825MG

--

Img

MilliporeSigma™

55-555-55MG

--

Img

MilliporeSigma™

49-200-010MG

--

Img

MilliporeSigma™

52-652-35MG

--

Img

MilliporeSigma™

57-312-110MG

--

Img

MilliporeSigma™

52-828-110MG

--

Img

MilliporeSigma™

50-616-35MG

--

Img

MilliporeSigma™

50-619-010MG

--

Description

  • A cell-permeable sulfonamido-benzamide-based allosteric regulator that stimulates DNA binding and recombinase activities of hRAD51 by locking hRAD51 in an active conformation without affecting its active site ATP hydrolysis
  • Although RS-1 enhances hRAD51 filament formation on ssDNA with or without the cofactor NTP, active filaments and recombinase activity are only induced in the presence of ATP or AMP-PNP, but not with ADP or no cofactors
  • Shown to promote resistance of primary human neonatal dermal fibroblasts to Cisplatin- (Cat
  • No
  • 232120) induced death in a dose-dependent manner
  • RS-1 is inactive toward related DNA strand exchange proteins scRAD5 and scDMC1 of yeast origin or E
  • coli RedA.This HDR (homology-directed repair) enhancer, is shown to significantly increase both Cas9 and TALEN-mediated knock-in efficiencies.