N2876

Neuraminidase from Clostridium perfringens (C. welchii)

Suitable for manufacturing of diagnostic kits and reagents, Type V, lyophilized powder

Manufacturer: Sigma Aldrich

CAS Number: 9001-67-6

Synonym(S): Acyl-neuraminyl Hydrolase, Receptor-destroying enzyme, Sialidase

Select a Size

Pack Size SKU Availability Price
2.5 UNITS N2876-2.5-UNITS In Stock ₹ 6,227.10
6 UNITS N2876-6-UNITS In Stock ₹ 7,237.20
25 UNITS N2876-25-UNITS In Stock ₹ 17,105.10
250 UNITS N2876-250-UNITS In Stock ₹ 1,27,150.50
625 UNITS N2876-625-UNITS In Stock ₹ 1,83,316.50

N2876 - 2.5 UNITS

₹ 6,227.10

In Stock

Quantity

1

Base Price: ₹ 6,227.10

GST (18%): ₹ 1,120.878

Total Price: ₹ 7,347.978

Quality Level

300

type

Type V

form

lyophilized powder

specific activity

≥0.1 units/mg solid (using mucin)≥1.3 units/mg solid (using 4MU-NANA)

application(s)

diagnostic assay manufacturing

foreign activity

Protease and NAN-aldolase, present

shipped in

dry ice

storage temp.

−20°C

Gene Information

Clostridium perfringens str. 13 ... nanI(988807)

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Description

  • General description: Neuraminidase enzymes are hydrolase enzymes that promote influenza virus release from infected cells and facilitate virus spread.
  • Application: Neuraminidase from Clostridium perfringens has been used in a study to assess binding with human T lymphocytes in sheep pretreated with neuraminidase. [1] It has also been used in a study to investigate the effect of bile salts on the action of hydrolysis by neuraminidase. [2]
  • Biochem/physiol Actions: Neuraminidase can increase aggregation in certain cell lines by removing exposed negatively charged sialic acid residues on the cell surface. [3]
  • Unit Definition: One unit will liberate 1.0 micromole of N-acetyl neuraminic acid per minute at pH 5.0 at 37 °C using bovine submaxillary mucin.One unit will hydrolyze 1.0 micromole of 2′-(4-methylumbelliferyl)-a-D-N-actetylneuraminic acid per minute at pH 5.0 at 37 °C (using 4MU-NANA as a substrate)
  • Preparation Note: Prepared by salt fractionation.
  • Analysis Note: Package sizes based on 4MU-NANA units

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves