N5631

Neuraminidase from Clostridium perfringens (C. welchii)

Type VIII, lyophilized powder, 10-20 units/mg protein (using 4MU-NANA), 3.5-8.0 units/mg protein (mucin)

Manufacturer: Sigma Aldrich

CAS Number: 9001-67-6

Synonym(S): Acyl-neuraminyl Hydrolase, Receptor-destroying enzyme, Sialidase

Select a Size

Pack Size SKU Availability Price
1 UNIT N5631-1-UNIT In Stock ₹ 18,192.90
5 UNITS N5631-5-UNITS In Stock ₹ 58,818.90
10 UNITS N5631-10-UNITS In Stock ₹ 96,703.20
50 UNITS N5631-50-UNITS In Stock ₹ 3,30,746.70

N5631 - 1 UNIT

₹ 18,192.90

In Stock

Quantity

1

Base Price: ₹ 18,192.90

GST (18%): ₹ 3,274.722

Total Price: ₹ 21,467.622

type

Type VIII

Quality Level

200

form

lyophilized powder

specific activity

10-20 units/mg protein (using 4MU-NANA)3.5-8.0 units/mg protein (mucin)

composition

Protein, ≥85% biuret

foreign activity

Protease and NAN-aldolase, present

storage temp.

−20°C

Gene Information

Clostridium perfringens str. 13 ... nanI(988807)

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Description

  • General description: Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.
  • Application: Neuraminidase from Clostridium perfringens has been used in a study to assess the binding characteristics of iota toxin by fluorescence-activated cytometry. [1] It has also been used in a study to investigate the distribution of neuraminidase among food poisoning strains. [2]
  • Biochem/physiol Actions: Neuraminidase cleavage of sialic acid groups has been used to study recognition by antibodies of glycoprotein structures. The use of neuraminidase in the estimation of N-acetylneuraminic acid was compared favorably to two other methods.
  • Unit Definition: One unit will liberate 1.0 micromole of N-acetyl neuraminic acid per minute at pH 5.0 at 37 °C using bovine submaxillary mucin.One unit will hydrolyze 1.0 micromole of 2′-(4-methylumbelliferyl)-a-D-N-actetylneuraminic acid per minute at pH 5.0 at 37 °C (using 4MU-NANA as a substrate)
  • Preparation Note: Chromatographically purified from Type V (N 2876)
  • Analysis Note: Package sizes based on 4MU-NANA units

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves