80126
N-tert-Butyl-α-phenylnitrone
for ESR-spectroscopy
Manufacturer: Supelco
CAS Number: 3376-24-7
Synonym(S): N-Benzylidene-tert-butylamine N-oxide, PBN, Phenyl N-t-butylnitrone
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 80126-1-G | In Stock | ₹ 23,089.73 |
80126 - 1 G
In Stock
Quantity
1
Base Price: ₹ 23,089.73
GST (18%): ₹ 4,156.151
Total Price: ₹ 27,245.881
grade
for ESR-spectroscopy
Quality Level
100
Assay
≥99.5% (HPLC)
form
powder
mp
72-74 °C73-74 °C (lit.)
solubility
chloroform: 50 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(C)(C)[N+](\[O-])=C\c1ccccc1
InChI
1S/C11H15NO/c1-11(2,3)12(13)9-10-7-5-4-6-8-10/h4-9H,1-3H3/b12-9-
InChI key
IYSYLWYGCWTJSG-XFXZXTDPSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Enzo Life Sciences PBN, (1g), CAS Number: 3376-24-7 | -- | ₹ 5,903.64 | |
| | tert-Butyl(benzylidene)amine N-oxide | -- | ₹ 513.36 - ₹ 75,036.12 | |
| | 3376-24-7 | (Z)-N-tert-butyl-1-phenylmethenimine oxide | -- | ₹ 2,481.24 - ₹ 91,891.44 |
Related Products
Description
- Application: N-tert-Butyl-a-phenylnitrone was used as spin trapping agent during measurement of scavenging rate constant of carotenoid using EPR spin-trapping technique.[1] This reagent helps in obtaining a six-line ESR spectrum and hyperfine coupling constants, confirming the presence of carbon-based radical in uric acid and peroxynitrite, using electron spin resonance spectroscopy and liquid chromatography mass spectrometry.[2]
- Biochem/physiol Actions: N-tert-butyl-α-phenylnitrone (PBN) is a commonly used free-radical spin trap. It has been shown to reduce the number of emboli-induced cerebral microinfarctions in the rabbit cortex and prevent neoplasia by its radical scavenging activity and its ability to inhibit cyclooxygenase-2 activity. Reported to inhibit the induction of nitric oxide synthase (iNOS), thereby preventing the overproduction of nitric oxide (NO). PBN in a dose of 100 mg/kg i.p. reduced necrosis of the substantia nigra, pars reticulate in flurothyl-induced status epilepticus in rats. It protects against some types of post-trauma epileptogenic events in an animal model of epilepsy. The lethal dose of PBN in rats was found to be approximately 100 mg/100 g body weight (0.564 mmol/100Å g).
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable