K1734

Thermo Scientific™ GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1734-Each-of-1 In Stock ₹ 9,05,224.80

K1734 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Accession Number

NM_000710

Cell State

Dividing Cells

Detection Method

Fluorescence

Gene Symbol

BDKRB1

Product Line

GeneBLAzer™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

CHO-K1

Druggable Target

GPCR

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 cells• GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ BDKRB1-NFAT-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application)

FRET

Population Status

Single Cell Clone Origin

Quantity

2 x 106Cells

Target Entry

BDKRB1

System Type

GeneBLAzer™

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Description

  • GeneBLAzer™ BDKRB1-NFAT- bla CHO-K1 cells contain the human Bradykinin Receptor 1 (BDKBR1) stably integrated into the CellSensor™ NFAT- bla CHO-K1 cell line
  • CellSensor™ NFAT- bla CHO-K1 cells (Cat
  • No
  • K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element
  • The GeneBLAzer™ BDKRB1-NFAT- bla CHO-K1 cells are functionally validated for Z' and EC 50 concentrations of [Lys-des-Arg9]-Bradykinin
  • In addition, GeneBLAzer™ BDKRB1-NFAT- bla CHO-K1 cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary
  • The Bradykinin-BDKRB1 receptor has been implicated in inflammation and pain
  • Preclinical evidence demonstrates that interruption of BDKRB1 receptor function causes analgesia under a variety of conditions and has been well established using selective antagonists and genetically modified mice
  • For Academic pricing please login or contact us at discoverysciences@invitrogen.com.