A3835

Ascomycin from Streptomyces hygroscopicus var. ascomyceticus

Manufacturer: Sigma Aldrich

CAS Number: 104987-12-4

Synonym(S): Changchuanmycin, FK-520, FR900520, Immunomycin, L 683590

Select a Size

Pack Size SKU Availability Price
1 MG A3835-1-MG In Stock ₹ 31,868.80

A3835 - 1 MG

₹ 31,868.80

In Stock

Quantity

1

Base Price: ₹ 31,868.80

GST (18%): ₹ 5,736.384

Total Price: ₹ 37,605.184

form

powder

Quality Level

200

greener alternative product score

old score: 59new score: 54Find out more about DOZN™ Scoring

greener alternative product characteristics

Designing Safer ChemicalsDesign for Energy EfficiencyLearn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

antibiotic activity spectrum

fungi

greener alternative category

, Re-engineered

Mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

CCC1\C=C(C)\C[C@H](C)C[C@H](OC)C2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)OC([C@H](C)[C@@H](O)CC1=O)\C(C)=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC

Other Options

Image Product Name Manufacturer Price Range
Sigma Aldrich Fine Chemicals Biosciences Ascomycin from Streptomyces hygroscopicus var. ascomyceticus | 104987-12-4 | MFCD06198665 | 1MG
-- ₹ 29,556.70
eMolecules​ Ascomycin | 104987-12-4 | | 1g
-- ₹ 55,689.29
Ascomycin from Streptomyces hygroscopicus var. ascomyceticus
-- ₹ 31,868.80
Ascomycin
-- ₹ 5,646.96 - ₹ 8,812.68
104987-12-4 | Ascomycin
-- ₹ 2,994.60 - ₹ 1,19,955.12

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Description

  • General description: Ascomycin (FK520) is a macrolide and macrolactone antibiotic isolated from the soil bacterium, Streptomyces hygroscopicus var. ascomyceticus. Ascomycin is a C21 ethyl analog of the macrolide tacrolimus (FK-506). It is a 23-membered polyketide macrolide.[1]
  • Biochem/physiol Actions: Ascomycin is a strong immunosuppressant. It inhibits allogenic T-lymphocyte proliferation and can bind with high affinity to FKBP and inhibits calcineurin phosphatase in the nM range.
  • Linkage: An FK506 analog with an ethyl rather than an allyl group at position 21.

SAFETY INFORMATION

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves