A8674
Antimycin A from Streptomyces sp.
Manufacturer: Sigma Aldrich
CAS Number: 1397-94-0
Synonym(S): Antipiricullin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 MG | A8674-25-MG | In Stock | ₹ 9,406.93 |
| 50 MG | A8674-50-MG | In Stock | ₹ 15,588.00 |
| 100 MG | A8674-100-MG | In Stock | ₹ 26,120.73 |
A8674 - 25 MG
In Stock
Quantity
1
Base Price: ₹ 9,406.93
GST (18%): ₹ 1,693.247
Total Price: ₹ 11,100.177
form
powder
Quality Level
300
antibiotic activity spectrum
fungi
Mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
[H]C(=O)Nc1cccc(C(=O)N[C@H]2[C@@H](C)OC(=O)C(CCCCCC)[C@@H](OC(=O)CC(C)C)[C@H](C)OC2=O)c1O
InChI
1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
InChI key
UIFFUZWRFRDZJC-RBVQMQRASA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Antimycin A from Streptomyces sp. | -- | ₹ 9,406.93 - ₹ 26,120.73 |
Related Products
Description
- General description: Antimycin is an antibiotic[1] produced by Streptomyces species. [2] It inhibits mitochondrial electron transport chain complex III and favors reactive oxygen species (ROS) production, impairing mitochondrial depolarization.[3] It inhibits nitric oxide-mediated apoptosis and modulatescytochrome C release.[4] It suppresses tumorigenesis in lung cancer cells and could be a potential therapeutic agent.[5]Antimycin A serves as a positive control for superoxide generation.
- Application: Antimycin A from Streptomyces sp. has been used:as a respiratory chain inhibitor in neuronal cultures[6][7]in organello ATP production assay in Trypanosoma brucei cells[8]in respiration assay for papillary thyroid carcinoma (PTC) cell lines[9]
- Biochem/physiol Actions: Inhibitor of electron transfer at complex III. Induces apoptosis.
- Quality: A mixture of antimycins.
- Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Aquatic Acute 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves