Dicyanocobinamide
≥93%
Manufacturer: Sigma Aldrich
CAS Number: 27792-36-5
Synonym(S): Cobinamide dicyanide, Etiocobalamin, Factor B
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | C3021-10-MG | In Stock | ₹ 14,126.63 |
| 50 MG | C3021-50-MG | In Stock | ₹ 47,987.23 |
C3021 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 14,126.63
GST (18%): ₹ 2,542.793
Total Price: ₹ 16,669.423
biological source
synthetic (organic)
Quality Level
200
Assay
≥93%
form
powder
impurities
≤0.1% vitamin B12
color
purple to very dark purple
storage temp.
−20°C
SMILES string
N#C[Co]C#N.C[C@H](O)CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)C2N=C1C(C)=C3N=C(C=C4N=C(C(C)=C5N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O
InChI
1S/C48H73N11O8.2CN.Co/c1-23(60)22-55-38(67)16-17-45(6)29(18-35(52)64)43-48(9)47(8,21-37(54)66)28(12-15-34(51)63)40(59-48)25(3)42-46(7,20-36(53)65)26(10-13-32(49)61)30(56-42)19-31-44(4,5)27(11-14-33(50)62)39(57-31)24(2)41(45)58-43;2*1-2;/h19,23,26-29,43,59-60H,10-18,20-22H2,1-9H3,(H2,49,61)(H2,50,62)(H2,51,63)(H2,52,64)(H2,53,65)(H2,54,66)(H,55,67);;;/b30-19-,39-24-,40-25-;;;/t23-,26+,27+,28+,29-,43?,45+,46-,47-,48-;;;/m0.../s1
InChI key
NJATWHPHZUGTHR-GXEWULDJSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Dicyanocobinamide | -- | ₹ 14,126.63 - ₹ 47,987.23 | |
| | 27792-36-5 | COBINAMIDE DICYANIDE | -- | ₹ 17,796.48 |
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Description
- General description: Dicyanocobinamide, also known as factor b is a coenzyme B12 precursor. It has a corrin ring structure with four of the six coordination sites of the cobalt (Co) atom being the pyrrole nitrogen atoms.[1]
- Application: Dicyanocobinamide has been used for the crystallization of vitamin B12-binding protein (BtuF).[2] It has also been used for the destabilization of BtuCD-BtuF Interaction.[3]
- Biochem/physiol Actions: Dicyanocobinamide (Cbi) functions as a soluble guanylate cyclase (sGC) co-activator and targets the N-terminal regulatory regions. This action is similar to the effect of forskolin on adenylyl cyclases. Dicyanocobinamide elevates the intracellular cyclic guanosine monophosphate (cGMP) levels and exhibits vasorelaxant activity in rats.[1] It is used along with various cobalamins in studies of the inhibition of HIV-1 integrase and nitric oxide synthase.[4]