Concanamycin A
≥70% (HPLC), crystals, vacuolar-type v-ATPase inhibitor
Manufacturer: Sigma Aldrich
CAS Number: 80890-47-7
Synonym(S): Folimycin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 μG | C9705-25-μG | In Stock | ₹ 24,150.58 |
| 0.1 MG | C9705-0.1-MG | In Stock | ₹ 67,569.65 |
C9705 - 25 μG
In Stock
Quantity
1
Base Price: ₹ 24,150.58
GST (18%): ₹ 4,347.104
Total Price: ₹ 28,497.684
Quality Level
200
Assay
≥70% (HPLC)
form
solid film
antibiotic activity spectrum
viruses
Mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
CCC1C(O)C(C)C\C(C)=C\C=C\C(OC)C(OC(=O)\C(OC)=C\C(C)=C\C(C)C1O)C(C)C(O)C(C)[C@]2(O)C[C@@H](O[C@H]3C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O3)[C@H](C)C(O2)\C=C\C
InChI
1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26?,27?,28-,29?,30?,31-,32?,33-,34?,35?,37-,38+,39?,40?,41?,42?,43-,46+/m1/s1
InChI key
DJZCTUVALDDONK-LWLXYWDNSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Concanamycin A >=70% (HPLC) | 80890-47-7 | MFCD00210037 | 0.1MG | -- | ₹ 61,989.93 | |
| | Concanamycin A | -- | ₹ 24,150.58 - ₹ 67,569.65 | |
| | 80890-47-7 | Concanamycin A | -- | ₹ 21,047.76 |
Related Products
Description
- General description: Chemical structure: macrolide
- Application: Concanamycin A has been used: as a lysosomal inhibitor in young and old fibroblasts[3] as a vacuolar-type H+-ATPase inhibitor in presynaptic vesicles[4]as a lysosomal acidification blocker in HepG2 hepatocytes cells[5]
- Biochem/physiol Actions: Concanamycin A (ConA) inhibits acidification of organelles[1] and perforin-mediated cytotoxicity.[6] It is a vacuolar-type v-ATPase inhibitor.[7] ConA possesses antiprotozoal and antineoplastic properties.[2] It mediates inhibition of the negative factor (Nef) protein of the human immunodeficiency virus.[1]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves