C8645

Cinoxacin

Manufacturer: Sigma Aldrich

CAS Number: 28657-80-9

Synonym(S): 1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid

Select a Size

Pack Size SKU Availability Price
5 G C8645-5-G In Stock ₹ 41,308.20

C8645 - 5 G

₹ 41,308.20

In Stock

Quantity

1

Base Price: ₹ 41,308.20

GST (18%): ₹ 7,435.476

Total Price: ₹ 48,743.676

form

powder or crystals

Quality Level

200

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

DNA synthesis | interferesenzyme | inhibits

SMILES string

CCN1N=C(C(O)=O)C(=O)c2cc3OCOc3cc12

InChI

1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)

InChI key

VDUWPHTZYNWKRN-UHFFFAOYSA-N

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Description

  • General description: Chemical structure: quinolone
  • Application: Cinoxacin was used to study the rat renal organic anion transporter 1 (OAT1).[1] It is used to study fluoroquinolone-resistant Streptococcus pyogenes.[2]
  • Biochem/physiol Actions: Cinoxacin is a synthetic antimicrobial agent that interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. The mechanism of action of cinoxacin is comparable to nalidixic acid. Cinoxacin is effective against Gram-negative bacteria and is often used to treat urinary tract infections caused by E. coli, Proteus mirabilis, Proteus vulgaris and Klebsiella sp.[3]
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves