L8912

L-Leucine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Manufacturer: Sigma Aldrich

CAS Number: 61-90-5

Synonym(S): (S)-Leucine, (S)-2-Amino-4-methylpentanoic acid

Select a Size

Pack Size SKU Availability Price
10 MG L8912-10-MG In Stock ₹ 2,403.15
25 G L8912-25-G In Stock ₹ 5,130.00
100 G L8912-100-G In Stock ₹ 17,731.35
1 KG L8912-1-KG In Stock ₹ 82,400.00

L8912 - 10 MG

₹ 2,403.15

In Stock

Quantity

1

Base Price: ₹ 2,403.15

GST (18%): ₹ 432.567

Total Price: ₹ 2,835.717

biological source

non-animal source

Quality Level

300

Agency

USP/NFmeets EP testing specificationsmeets JP testing specificationsmeets USP testing specifications

Assay

98.5-101.0%

form

powder

optical activity

[α]20/D 14.9 to 16.0°, c = 4 in 6 M HCl[α]25/D 14.9 to 17.3 °, c = 4 in 6 M HCl

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

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Description

  • General description: Leucine is a non-glucogenic, and essential amino acid. It is a branched-chain amino acid that is a structural component of proteins.[1]
  • Application: L-Leucine has been used:as a hypertrophic agent to monitor its effects on myotubes.[2]as a component of PMG media for culturing yeast.[3] in myotube protein synthesis analysis in skeletal muscle cells.[4] to study its effects on hepatic lipid metabolism.[5]
  • Biochem/physiol Actions: Leucine plays a role in intracellular signaling, gene transcription, and translation. It promotes the synthesis of protein by activating the mammalian target of the rapamycin (mTOR) signaling pathway in placental cells, skeletal muscles, and adipose tissue.[6] Leucine inhibits protein degradation and promotes mitochondrial biogenesis, glucose metabolism, and fatty acid oxidation to provide energy for protein synthesis.[1]
  • Other Notes: For additional information on our range of Biochemicals, please complete this form.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves