T2877

3,3′,5-Triiodo-L-thyronine

≥95% (HPLC), powder

Manufacturer: Sigma Aldrich

CAS Number: 6893-02-3

Synonym(S): O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Liothyronine, T3

Select a Size

Pack Size SKU Availability Price
100 MG T2877-100-MG In Stock ₹ 7,187.80
250 MG T2877-250-MG In Stock ₹ 15,642.13
500 MG T2877-500-MG In Stock ₹ 23,382.00
1 G T2877-1-G In Stock ₹ 35,321.98
5 G T2877-5-G In Stock ₹ 1,51,842.28

T2877 - 100 MG

₹ 7,187.80

In Stock

Quantity

1

Base Price: ₹ 7,187.80

GST (18%): ₹ 1,293.804

Total Price: ₹ 8,481.604

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

Assay

≥95% (HPLC)

form

powder

optical activity

[α]25/D +23.0°, c = 2 in 1 N HCl: ethanol, 1:2

technique(s)

transfection: suitable

mp

234-238 °C (lit.)

solubility

4 M NH4OH in methanol: 5 mg/mL, clear to very slightly hazy, colorless to light yellow

shipped in

ambient

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Description

  • Application: 3,3′,5-Triiodo-L-thyronine can be used for Insulin-like growth factor I assays performed by using a double antibody radioimmunoassay.[1] The product can also be used for in vitro transfection of 293T cells.[2]
  • Biochem/physiol Actions: 3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine enhances mood and neuropsychological function.[3] The product also positively regulates the hepatic FGF21 expression[2] and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation. Additionally, the product facilitates the normal body growth in children and is pivotal for central nervous system maturation in foetus.
  • Preparation Note: 3,3′,5-Triiodo-L-thyronine dissolves in 4M NH4OH in MeOH at 5 mg/ml to yield a colorless to light yellow, clear to very slightly hazy solution.
  • Other Notes: This product has not been tested for cell culture. A sterile version is offered that is suitable for cell culture. The T5516 is a sterile preparation that is cell culture tested. Please review the product page for product T2877

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1

Target Organs

Thyroid,Cardio-vascular system,Kidney

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves