T3535
Calcitonin human
≥97% (HPLC), powder
Manufacturer: Sigma Aldrich
CAS Number: 21215-62-3
Synonym(S): Calcitonin M, human C carcinoma, Calcitonin, human reduced cyclic (1→7)-disulfide, Thyrocalcitonin, hCT
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | T3535-1-MG | In Stock | ₹ 1,41,158.00 |
T3535 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 1,41,158.00
GST (18%): ₹ 25,408.44
Total Price: ₹ 1,66,566.44
biological source
synthetic (organic)
Quality Level
200
sterility
non-sterile
Assay
≥97% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
1% acetic acid: 1.00-1.04 mg/mL, clear, colorlesswater: 1.00-1.04 mg/mL, clear, colorless
UniProt accession no.
P06881P01258
shipped in
ambient
storage temp.
−20°C
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Calcitonin human >=97% (HPLC), powder | 21215-62-3 | MFCD00167520 | 1MG | -- | ₹ 1,50,431.59 | |
| | Echelon Biosciences Research Labs Calcitonin (human), cyclic - 5 mg, CAS#: 21215-62-3 | -- | ₹ 60,562.79 | |
| | Tocris Bioscience™ Calcitonin (human) | -- | ₹ 34,694.58 | |
| | 21215-62-3 | Calcitonin, Human | -- | ₹ 17,368.68 - ₹ 61,432.08 |
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Description
- Amino Acid Sequence: Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2 [Disulfide Bridge: 1−7]
- Application: Calcitonin human has been used as a positive control in in vivo study of HLA-A(*) 02.01 (HHD) mice injected with PTH-rP peptides.[1] The product has also be used as a test compound for studying the effects of calcitonin deficiency and calcitonin substitution on particle-induced osteolysis in Calca -/- mice.[2]
- Biochem/physiol Actions: Calcitonin, also referred to as thyrocalcitonin, is a 32 amino acid peptide hormone, which is present abundantly in seminal plasma compared to serum. It acts as a first messenger and hence regulates the the production of cAMP as well as mammalian sperm function. It also facilitates the regulation of different isoforms of adenylyl cyclase.[4]
- Other Notes: 32 amino acid polypeptide, 8 of which are conserved across all species.
- Preparation Note: Calcitonin human dissolves in 1% acetic acid as well as in water at 1 mg/ml to yield a clear, colorless solution.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves