48-421-0
Tocris Bioscience™ BIX 02189
Manufacturer: Tocris Bioscience™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 48-421-0-Each-of-1 | In Stock | ₹ 27,892.56 |
48-421-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,892.56
GST (18%): ₹ 5,020.661
Total Price: ₹ 32,913.221
Purity
>98%
Product Type
BIX 02189
Inhibitors
BIX 02189
Quantity
10 mg
Molecular Weight (g/mol)
440.54
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Description
- BIX 02189 is a selective MEK5 and ERK5 inhibitor (IC50 values are 1.5 and 59 nM respectively)
- Inhibits sorbitol-induced ERK5 phosphorylation in HeLa cells
- Selective for MEK5 and ERK5 over MEK1/2, ERK1/2 and a panel of 87 kinases
- Induces apoptosis in acute myeloid leukemia tumor cells.