5545741
Tocris Bioscience™ CGP 71683 hydrochloride
Highly selective and potent non-peptide NPY Y5 receptor antagonist
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
CGP 71683 hydrochloride
Molecular Weight (g/mol)
512.07
Inhibitors
CGP 71683 hydrochloride
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Description
- Extremely selective, non-peptide NPY Y5 receptor antagonist
- Displays > 1000-fold selectivity over Y1, Y2 and Y4 receptors; IC50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y5, Y1, Y2 and Y4 receptors respectively
- Potently inhibits NPY-induced food intake following i.p
- administration in diabetic, free-feeding and fasted rats.